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Lens Connexin Channels Have Differential Permeability to the Second Messenger cAMP.

Virginijus Valiunas | Peter R Brink | Thomas W White
Investigative ophthalmology & visual science | 2019

Gap junction channels exhibit connexin specific biophysical properties, including the selective intercellular passage of larger solutes, such as second messengers. Here, we have examined the cyclic nucleotide permeability of the lens connexins, which could influence events like epithelial cell division and differentiation.

Pubmed ID: 31529078

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: NEI NIH HHS, United States
    Id: R01 EY013163
  • Agency: NEI NIH HHS, United States
    Id: R01 EY026911
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM088180
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM088181

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GraphPad Prism (tool)

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HeLa (tool)

RRID:CVCL_0030

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