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LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2.

Mu Xu | Xueni Xu | Bei Pan | Xiaoxiang Chen | Kang Lin | Kaixuan Zeng | Xiangxiang Liu | Tao Xu | Li Sun | Jian Qin | Bangshun He | Yuqin Pan | Huiling Sun | Shukui Wang
Molecular cancer | 2019

Emerging studies suggest that long non-coding RNAs (lncRNAs) play crucial roles in colorectal cancer (CRC). Here, we report a lncRNA, SATB2-AS1, which is specifically expressed in colorectal tissue and is significantly reduced in CRC. We systematically elucidated its functions and possible molecular mechanisms in CRC.

Pubmed ID: 31492160

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