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Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer.

Taichi Kuwahara | Shoichi Hazama | Nobuaki Suzuki | Shin Yoshida | Shinobu Tomochika | Yuki Nakagami | Hiroto Matsui | Yoshitaro Shindo | Shinsuke Kanekiyo | Yukio Tokumitsu | Michihisa Iida | Ryouichi Tsunedomi | Shigeru Takeda | Shigefumi Yoshino | Naoko Okayama | Yutaka Suehiro | Takahiro Yamasaki | Tomonobu Fujita | Yutaka Kawakami | Tomio Ueno | Hiroaki Nagano
British journal of cancer | 2019

CD3 +  and CD8 + T-cell infiltration were reported as positive predictive markers of survival in colorectal cancer (CRC) patients. Here, we demonstrate the prognostic significance of CD4 + and FOXP3 + T-cell densities in CRC.

Pubmed ID: 31488881

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QIAGEN (tool)

RRID:SCR_008539

A commercial organization which provides assay technologies to isolate DNA, RNA, and proteins from any biological sample. Assay technologies are then used to make specific target biomolecules, such as the DNA of a specific virus, visible for subsequent analysis.

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