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16/18 genotyping in triage of persistent human papillomavirus infections with negative cytology in the English cervical screening pilot.

Matejka Rebolj | Adam R Brentnall | Christopher Mathews | Karin Denton | Miles Holbrook | Tanya Levine | Alexandra Sargent | John Smith | John Tidy | Xenia Tyler | Henry Kitchener | HPV Pilot Steering Group
British journal of cancer | 2019

In the English pilot of primary cervical screening with high-risk human papillomavirus (HR-HPV), we exploited natural viral clearance over 24 months to minimise unnecessary referral of HR-HPV+ women with negative cytology. Three laboratories were permitted to use 16/18 genotyping to select women for referral at 12-month recall. We estimated the clinical impact of this early genotyping referral.

Pubmed ID: 31409912

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Associated grants

  • Agency: Cancer Research UK, United Kingdom
    Id: C8162/A16892
  • Agency: Cancer Research UK, United Kingdom
    Id: C569/A16891

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Abbott Diagnostics (tool)

RRID:SCR_008392

Company offering a broad range of instrument systems and diagnostic tests for hospitals, reference labs, blood banks, physician offices and clinics to aid in the diagnosis of a range of serious health issues such as infectious diseases, cancer, and diabetes, as well as monitor other important indicators of health.

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