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Simvastatin downregulates adipogenesis in 3T3-L1 preadipocytes and orbital fibroblasts from Graves' ophthalmopathy patients.

B Shahida | P Sahlstrand Johnson | R Jain | H Brorson | P Åsman | M Lantz | T Planck
Endocrine connections | 2019

Smoking is a strong risk factor for the development of Graves' ophthalmopathy (GO). Immediate early genes (IEGs) are overexpressed in patients with active GO compared to healthy controls. The aim of this study was to study the effects of tobacco smoking and simvastatin on preadipocytes and orbital fibroblasts (OFs) in the adipogenic process.

Pubmed ID: 31394503

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This is a list of tools and resources that we have found mentioned in this publication.


3T3-L1 (tool)

RRID:CVCL_0123

Cell line 3T3-L1 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)

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3T3-L1 (tool)

RRID:CVCL_0123

Cell line 3T3-L1 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)

View all literature mentions