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Galectin-3 as a candidate upstream biomarker for quantifying risks of myocardial ageing.

Bryan M H Keng | Fei Gao | See Hooi Ewe | Ru San Tan | Louis L Y Teo | Bei Qi Xie | Woon-Puay Koh | Angela S Koh
ESC heart failure | 2019

Galectin-3 (Gal-3) is implicated in the pathogenesis of heart failure and is also influenced by ageing. This study aims to determine the extent to which Gal-3 levels estimate odds of myocardial dysfunction in ageing cohorts, 'upstream' prior to clinical disease.

Pubmed ID: 31392851

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Associated grants

  • Agency: NIH HHS, United States
    Id: UM1 CA182876
  • Agency: NIH HHS, United States
    Id: NIH R01 CA144034
  • Agency: SingHealth Foundation, International
  • Agency: Estate of Tan Sri Khoo Teck Puat, International
  • Agency: Duke-NUS Medical School, International
  • Agency: Hong Leong Foundation, International
  • Agency: National Medical Research Council, International
    Id: MOH-000153
  • Agency: National Medical Research Council, International
    Id: NMRC/TA/0031/2015

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