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Quantitative investigation of factors relevant to the T cell spot test for tuberculosis infection in active tuberculosis.

Kui Li | Caiyong Yang | Zicheng Jiang | Shengxi Liu | Jun Liu | Chuanqi Fan | Tao Li | Xuemin Dong
BMC infectious diseases | 2019

Previous qualitative studies suggested that the false negative rate of the T cell spot test for tuberculosis infection (T-SPOT.TB) is associated with many risk factors in tuberculosis patients. However, more precise quantitative studies are lacking. The purpose of this study was to investigate the factors affecting quantified spot-forming cells (SFCs) to early secreted antigenic target 6 kDa (ESAT-6) or culture filtrate protein 10 kDa (CFP-10) in patients with active tuberculosis.

Pubmed ID: 31357953

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RRID:SCR_002865

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RRID:SCR_001905

Software environment and programming language for statistical computing and graphics. R is integrated suite of software facilities for data manipulation, calculation and graphical display. Can be extended via packages. Some packages are supplied with the R distribution and more are available through CRAN family.It compiles and runs on wide variety of UNIX platforms, Windows and MacOS.

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