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Activated M2 Macrophages Contribute to the Pathogenesis of IgG4-Related Disease via Toll-like Receptor 7/Interleukin-33 Signaling.

Noriko Ishiguro | Masafumi Moriyama | Katsuhiro Furusho | Sachiko Furukawa | Takuma Shibata | Yusuke Murakami | Akira Chinju | A S M Rafiul Haque | Yuka Gion | Miho Ohta | Takashi Maehara | Akihiko Tanaka | Masaki Yamauchi | Mizuki Sakamoto | Keita Mochizuki | Yuko Ono | Jun-Nosuke Hayashida | Yasuharu Sato | Tamotsu Kiyoshima | Hidetaka Yamamoto | Kensuke Miyake | Seiji Nakamura
Arthritis & rheumatology (Hoboken, N.J.) | 2020

IgG4-related disease (IgG4-RD) is a unique inflammatory disorder in which Th2 cytokines promote IgG4 production. In addition, recent studies have implicated the Toll-like receptor (TLR) pathway. This study was undertaken to examine the expression of TLRs in salivary glands (SGs) from patients with IgG4-RD.

Pubmed ID: 31339007

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

None

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Novus Biologicals (tool)

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C57BL/6J (tool)

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C57BL/6N (tool)

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laboratory mouse with name C57BL/6N from MGI.

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C57BL/6N (tool)

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laboratory mouse with name C57BL/6N from MGI.

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