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Development of a Humanized Murine Model for the Study of Oxalobacter formigenes Intestinal Colonization.

Amanda M Pebenito | Menghan Liu | Lama Nazzal | Martin J Blaser
The Journal of infectious diseases | 2019

Oxalobacter formigenes are bacteria that colonize the human gut and degrade oxalate, a component of most kidney stones. Findings of clinical and epidemiological studies suggest that O. formigenes colonization reduces the risk for kidney stones. We sought to develop murine models to allow investigating O. formigenes in the context of its native human microbiome.

Pubmed ID: 31328778

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: U54 DK083908
  • Agency: NCI NIH HHS, United States
    Id: P30 CA016087

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