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Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients (COMIC): a pilot randomised controlled trial protocol.

Kimberley Lewis | Sarah Culgin | Roman Jaeschke | Dan Perri | Corry Marchildon | Kelly Hassall | Thomas Piraino | Lehana Thabane | Yousef Almubarak | Mohammed S Alshahrani | Bram Rochwerg | Bandar Baw | Wojciech Szczeklik | Tim Karachi | Waleed Alhazzani | GUIDE Group
BMJ open | 2019

Endotracheal intubation and invasive mechanical ventilation are lifesaving interventions that are commonly performed in the intensive care unit (ICU). Laryngeal oedema is a known complication of intubation that may cause airway obstruction in a patient on extubation. To date, the only test available to predict this complication is the cuff leak test (CLT); however, its diagnostic accuracy and utility remains uncertain. Herein, we report the protocol for the CuffLeak and AirwayObstruction in MechanicallyVentilated ICU Patients (COMIC) pilottrial.

Pubmed ID: 31326936

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RRID:SCR_003445

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