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miR-34a as hub of T cell regulation networks.

Martin Hart | Barbara Walch-Rückheim | Lena Krammes | Tim Kehl | Stefanie Rheinheimer | Tanja Tänzer | Birgit Glombitza | Martina Sester | Hans-Peter Lenhof | Andreas Keller | Eckart Meese
Journal for immunotherapy of cancer | 2019

Micro(mi)RNAs are increasingly recognized as central regulators of immune cell function. While it has been predicted that miRNAs have multiple targets, the majority of these predictions still await experimental confirmation. Here, miR-34a, a well-known tumor suppressor, is analyzed for targeting genes involved in immune system processes of leucocytes.

Pubmed ID: 31311583

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