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Pre-existing Antineuraminidase Antibodies Are Associated With Shortened Duration of Influenza A(H1N1)pdm Virus Shedding and Illness in Naturally Infected Adults.

Hannah E Maier | Raffael Nachbagauer | Guillermina Kuan | Sophia Ng | Roger Lopez | Nery Sanchez | Daniel Stadlbauer | Lionel Gresh | Amy Schiller | Arvind Rajabhathor | Sergio Ojeda | Andrea F Guglia | Fatima Amanat | Angel Balmaseda | Florian Krammer | Aubree Gordon
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | 2020

Influenza causes a substantial burden worldwide, and current seasonal influenza vaccine has suboptimal effectiveness. To develop better, more broadly protective vaccines, a more thorough understanding is needed of how antibodies that target the influenza virus surface antigens, hemagglutinin (HA) (including head and stalk regions) and neuraminidase (NA), impact influenza illness and virus transmission.

Pubmed ID: 31300819

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: R01 AI120997
  • Agency: NIAID NIH HHS, United States
    Id: U01 AI088654
  • Agency: NIAID NIH HHS, United States
    Id: HHSN272201400006C
  • Agency: NIAID NIH HHS, United States
    Id: HHSN272201400008C

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R Project for Statistical Computing (tool)

RRID:SCR_001905

Software environment and programming language for statistical computing and graphics. R is integrated suite of software facilities for data manipulation, calculation and graphical display. Can be extended via packages. Some packages are supplied with the R distribution and more are available through CRAN family.It compiles and runs on wide variety of UNIX platforms, Windows and MacOS.

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