Searching the Resource Information Network
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
Large sample sizes are often required to detect statistically significant associations between pharmacogenetic markers and treatment response. Meta-analysis may be performed to synthesise data from several studies, increasing sample size and consequently power to detect significant genetic effects. However, performing robust synthesis of data from pharmacogenetic studies is often challenging due to poor reporting of key data in study reports. There is currently no guideline for the reporting of pharmacogenetic studies. The aim of this project is to develop the STrengthening the Reporting Of Pharmacogenetic Studies (STROPS) guideline. The STROPS guideline will facilitate the conduct of high-quality meta-analyses and thus improve the power to detect genetic associations.
Pubmed ID: 31300508
Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.
Public bibliographic database that provides access to citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. PubMed citations and abstracts include fields of biomedicine and health, covering portions of life sciences, behavioral sciences, chemical sciences, and bioengineering. Provides access to additional relevant web sites and links to other NCBI molecular biology resources. Publishers of journals can submit their citations to NCBI and then provide access to full-text of articles at journal web sites using LinkOut.
View all literature mentionsDelPhi provides numerical solutions to the Poisson-Boltzmann equation (both linear and nonlinear form) for molecules of arbitrary shape and charge distribution. The current version is fast, accurate, and can handle extremely high lattice dimensions. It also includes flexible features for assigning different dielectric constants to different regions of space and treating systems containing mixed salt solutions. DelPhi takes as input a coordinate file format of a molecule or equivalent data for geometrical objects and/or charge distributions and calculates the electrostatic potential in and around the system, using a finite difference solution to the Poisson-Boltzmann equation. DelPhi is a versatile electrostatics simulation program that can be used to investigate electrostatic fields in a variety of molecular systems. Features of DelPhi include solutions to mixtures of salts of different valence; solutions to different dielectric constants to different regions of space; and estimation of the best relaxation parameter at run time.
View all literature mentionsThe EQUATOR Network is an international initiative that seeks to enhance reliability and value of medical research literature by promoting transparent and accurate reporting of research studies. This goal will be achieved through: raising awareness of the crucial importance of good reporting of research becoming the recognised global centre providing resources, education and training relating to the reporting of health research and use of reporting guidelines assisting in the development, dissemination and implementation of reporting guidelines monitoring the status of the quality of reporting across health research literature conducting research relating to the quality of reporting The EQUATOR Network Resource Centre provides up-to-date resources related to health research reporting mainly for: authors of research articles journal editors and peer reviewers reporting guideline developers Other users that benefit from the knowledge of principles of good research reporting include representatives of research funders, research ethics committee members, individuals and organisations involved in research education. The resources on our website are regularly updated (see the date of the last update at the foot of each page). Sponsor. Core programme funding for 2007 - 2013 NHS National Library for Health NHS National Institute for Health Research NHS National Knowledge Service UK Medical Research Council Canadian Institutes of Health Research Scottish Chief Scientist Office Pan American Health Organization
View all literature mentions