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Ivermectin reverses the drug resistance in cancer cells through EGFR/ERK/Akt/NF-κB pathway.

Lu Jiang | Pan Wang | Ying-Jian Sun | Yi-Jun Wu
Journal of experimental & clinical cancer research : CR | 2019

Discovery and development of novel drugs that are capable of overcoming drug resistance in tumor cells are urgently needed clinically. In this study, we sought to explore whether ivermectin (IVM), a macrolide antiparasitic agent, could overcome the resistance of cancer cells to the therapeutic drugs.

Pubmed ID: 31215501

Research resources used in this publication

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Associated grants

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