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Expression of ICOSL is associated with decreased survival in invasive breast cancer.

Bin Wang | Huayong Jiang | Tingyang Zhou | Ning Ma | Wei Liu | Yajie Wang | Li Zuo
PeerJ | 2019

Inducible co-stimulator (ICOS) is a CD28-related molecule exclusively expressed on activated T cells and plays a critical role in modulating the immune response in breast cancer. The blockage of ICOS pathway has been shown to inhibit the activity of Type 2 T helper cells, thus potentially protecting against cancer growth. The current study aims to investigate the correlation between inducible co-stimulator ligand (ICOSL) expression in tumor tissues and the prognoses of patients with invasive breast cancer.

Pubmed ID: 31143539

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Abcam (tool)

RRID:SCR_012931

A commercial antibody supplier which supplies primary and secondary antibodies, biochemicals, proteins, peptides, lysates, immunoassays and other kits.

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