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Cathepsin C Interacts with TNF-α/p38 MAPK Signaling Pathway to Promote Proliferation and Metastasis in Hepatocellular Carcinoma.

Guo-Pei Zhang | Xiao Yue | Shao-Qiang Li
Cancer research and treatment | 2020

Although cathepsin C (CTSC) has been reported to maintain malignant biological properties in various cancers, its functions in hepatocellular carcinoma (HCC) remain obscure. We aimed to investigate the potential role of CTSC in HCC.

Pubmed ID: 31048666

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GeneCards (tool)

RRID:SCR_002773

Database of human genes that provides concise genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes. Information featured in GeneCards includes orthologies, disease relationships, mutations and SNPs, gene expression, gene function, pathways, protein-protein interactions, related drugs and compounds and direct links to cutting edge research reagents and tools such as antibodies, recombinant proteins, clones, expression assays and RNAi reagents.

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cBioPortal (tool)

RRID:SCR_014555

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RRID:SCR_018294

Web server for cancer and normal gene expression profiling and interactive analyses. Interactive web server for analyzing RNA sequencing expression data of tumors and normal samples from TCGA and GTEx projects, using standard processing pipeline. Provides customizable functions such as tumor or normal differential expression analysis, profiling according to cancer types or pathological stages, patient survival analysis, similar gene detection, correlation analysis and dimensionality reduction analysis.

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RRID:IMSR_JAX:002019

Mus musculus with name NU/J from IMSR.

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SMMC-7721 (tool)

RRID:CVCL_0534

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RRID:CVCL_0525

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RRID:CVCL_0525

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RRID:CVCL_0485

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RRID:CVCL_0027

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Hep 3B2.1-7 (tool)

RRID:CVCL_0326

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