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Atherosclerosis is as a systemic inflammatory disease associated with the activationof many mediators, including matrix metalloproteinases (MMPs), and may be amplified by abnormal high serum uric acid (UA) concentration (hyperuricemia, HU). The aim of the study was to determine the relationship between serum UA concentration and activity of MMPs and their correlation with the hypertension-mediated organ damage (HMOD) intensity.
Pubmed ID: 30994184
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Commercially available services for biomedical research. Includes the quantitative determination of the methylation level of selected epigenetic markers, designing and validation of primers and conditions for the multiplication of selected markers by PCR and determination of their methylation level by the pyrosequencing method. Service electro-optical laboratory equipment and offers specialized repair services: PCR thermal cyclers, Laboratory power supplies, ELISA plate readers.
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