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Reassessing the Safety Profile of Lesinurad in Combination with Xanthine Oxidase Inhibitor Therapy.

Fernando Perez-Ruiz | Tim L Jansen | Anne-Kathrin Tausche | Pascal Richette | Frédéric Lioté | Alexander K So | Austin Stack
Rheumatology and therapy | 2019

The rate of adverse renal events has been shown to be higher in patients treated with lesinurad plus a xanthine-oxidase inhibitor (XOI) than in patients treated only with a XOI. We reassessed the risks for various adverse renal events from a different perspective and devised a hypothesis to explain the results.

Pubmed ID: 30767124

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RRID:SCR_015044

Statistical software for ROC curve analysis. MedCalc performs several statistical tests such as method comparison, method evaluation, reference intervals, and meta-analysis.

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