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The adipo-fibrokine activin A is associated with metabolic abnormalities and left ventricular diastolic dysfunction in obese patients.

Judith Zeller | Carolin Krüger | Valeria Lamounier-Zepter | Sabine Sag | Christina Strack | Margareta Mohr | Thomas Loew | Gerd Schmitz | Lars Maier | Marcus Fischer | Andrea Baessler
ESC heart failure | 2019

Left ventricular diastolic dysfunction (LVDD) is common in obese subjects, and a relationship between epicardial adipose tissue (EAT), increased adipocytokines, and cardiovascular diseases has been reported. This study sought to examine as to whether the adipo-fibrokine activin A is a link between increased EAT, the metabolic syndrome (MetS), and LVDD in severely obese subjects.

Pubmed ID: 30729712

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