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Bufei Jianpi Granules Reduce Quadriceps Muscular Cell Apoptosis by Improving Mitochondrial Function in Rats with Chronic Obstructive Pulmonary Disease.

Jing Mao | Ya Li | Suyun Li | Jiansheng Li | Yange Tian | Suxiang Feng | Xuefang Liu | Qingqing Bian | Junzi Li | Yuanyuan Hu | Lanxi Zhang | Huige Ji
Evidence-based complementary and alternative medicine : eCAM | 2019

Cell apoptosis is an important mechanism underlying skeletal muscle dysfunction in chronic obstructive pulmonary disease (COPD) patients, and mitochondrial dysfunction is recognized as a central aspect contributing to skeletal muscle deterioration. Bufei Jianpi granules have been confirmed effective for improving motor function in COPD patients, but the specific mechanism for this improved function remains unknown. This study explored the mechanisms by which Bufei Jianpi granules improve cell apoptosis and mitochondrial dysfunction in COPD.

Pubmed ID: 30723509

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Thermo Fisher Scientific (tool)

RRID:SCR_008452

Commercial vendor and service provider of laboratory reagents and antibodies. Supplier of scientific instrumentation, reagents and consumables, and software services.

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Millipore (tool)

RRID:SCR_008983

An Antibody supplier

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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