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Effects of Jobelyn® on Isoniazid-Induced Seizures, Biomarkers of Oxidative Stress and Glutamate Decarboxylase Activity in Mice.

Stephen Asehinde | Abayomi Ajayi | Adewale Bakre | Osarume Omorogbe | Adaeze Adebesin | Solomon Umukoro
Basic and clinical neuroscience | 2018

Isoniazid-induced seizure, often described as Status Epilepticus (SE), is an emergency condition characterized by repeated convulsive episodes that responds poorly to the currently available anticonvulsant drugs. The current study aimed at ascertaining the effect of Jobelyn® (JB), an African dietary supplement, on seizures, altered oxidative stress, and glutamate decarboxylase activity induced by isoniazid in mice.

Pubmed ID: 30719253

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Swiss nude (tool)

RRID:MGI:5649767

laboratory mouse with name Swiss nude from MGI.

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