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Establishment and characterization of a patient-derived circulating lung tumor cell line in vitro and in vivo.

Zujun Que | Bin Luo | Zhiyi Zhou | Changsheng Dong | Yi Jiang | Lin Wang | Qihui Shi | Jianhui Tian
Cancer cell international | 2019

Circulating tumor cells (CTCs) have been described as a population of cells that may seed metastasis, which is a reliable target for the prevention of metastases in lung cancer patients at the early stage. The culturing of CTCs in vitro can be used to study the mechanism of lung cancer metastasis and to screen antimetastasis drugs. This study aims to establish CTC cell line in vitro and explore the potential mechanism of its metastasis.

Pubmed ID: 30718976

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