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The molecular mechanism for the pathogenesis of nonalcoholic fatty liver disease (NAFLD) remains elusive. Both farnesoid X receptor (FXR) signalling and endoplasmic reticulum (ER) stress contribute to the progression of NAFLD; however, it is not clear whether the actions of these two pathways are dependent on each other. Moreover, the pharmacological benefits and mechanism of betulinic acid (BA) in controlling metabolic syndrome and NAFLD are largely unknown.
Pubmed ID: 30635917
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This polyclonal targets PERK/EIF2AK3
View all literature mentionsThis monoclonal targets Cyp7a1
View all literature mentionsThis monoclonal targets Phospho-PERK (Thr980)
View all literature mentionsThis monoclonal targets eIF2alpha (Ser51)
View all literature mentionsThis recombinant monoclonal targets Insulin Receptor beta
View all literature mentionsThis polyclonal targets Phospho-Akt (Ser473)
View all literature mentionsThis polyclonal targets Phospho-IGF-I Receptor beta (Tyr1131)/Insulin Receptor beta (Tyr1146)
View all literature mentionsThis monoclonal targets Mouse SCD1
View all literature mentionsThis polyclonal targets eIF2 alpha
View all literature mentionsThis monoclonal targets Beta Actin
View all literature mentionsThis monoclonal targets BiP (C50B12) Rabbit mAb
View all literature mentionsThis polyclonal targets CHOP; GADD153
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
View all literature mentionsMus musculus with name B6.129X1(FVB)-Nr1h4tm1Gonz/J from IMSR.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsSoftware package used for interactive, or batched, statistical analysis in social science, health sciences and marketing. Software platform offers advanced statistical analysis, a library of machine-learning algorithms, text analysis, open-source extensibility, integration with big data and deployment into applications.Versions that were produced by SPSS Inc. before the IBM acquisition (Versions 18 and earlier) would be given origin or publisher of SPSS Inc. in Chicago.
View all literature mentionsPortal and searchable database of pharmacological information. Information is presented at two levels, the initial view or landing pages for each target family provide expert-curated overviews of the key properties and the available selective ligands and tool compounds. For selected targets, more detailed introductory chapters for each family are available along with curated information on the pharmacological, physiological, structural, genetic and pathophysiogical properties of each target.
View all literature mentionsCell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)
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