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Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study.

Kirsten van de Groep | Stefan Nierkens | Olaf L Cremer | Linda M Peelen | Peter M C Klein Klouwenberg | Marcus J Schultz | C Erik Hack | Tom van der Poll | Marc J M Bonten | David S Y Ong | MARS consortium
Critical care (London, England) | 2018

Cytomegalovirus (CMV) reactivation in previously immunocompetent critically ill patients is associated with increased mortality, which has been hypothesized to result from virus-induced immunomodulation. Therefore, we studied the effects of CMV reactivation on the temporal course of host response biomarkers in patients with sepsis.

Pubmed ID: 30563551

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Associated grants

  • Agency: Center for Translational Molecular Medicine, International
    Id: 041-201

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GraphPad Prism (tool)

RRID:SCR_002798

Statistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.

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