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Publication

Efflux inhibition by H2S confers sensitivity to doxorubicin-induced cell death in liver cancer cells.

Eric Stokes | Tian Shuang | Yanjie Zhang | Yanxi Pei | Ming Fu | Baoqing Guo | Amadeo Parissenti | Lingyun Wu | Rui Wang | Guangdong Yang
Life sciences | 2018

Hydrogen sulfide (H2S), an important gasotransmitter, is involved in a variety of cellular functions and pathophysiologic processes. Drug resistance due to alterations in drug trafficking and metabolism severely limits the effectiveness of cancer therapy. This study examined the role of H2S in drug resistance in liver cancer cells.

Pubmed ID: 30343125

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