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Melatonin promotes reduction in TNF levels and improves the lipid profile and insulin sensitivity in pinealectomized rats with periodontal disease.

Rodrigo Martins Dos Santos | Fernando Marani | Fernando Yamamoto Chiba | Maria Sara de Lima Coutinho Mattera | Thais VerĂ´nica Saori Tsosura | Gestter Willian Lattari Tessarin | Renato Felipe Pereira | Bianca Elvira Belardi | Beatriz Costa E Silva Pinheiro | Doris Hissako Sumida
Life sciences | 2018

This study aimed to investigate the effects of melatonin (ME) on insulin resistance (IR) and signaling (IS), proinflammatory cytokine levels, and lipid profiles in pinealectomyzed (PNX) rats with periodontal disease (PD).

Pubmed ID: 30321542

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