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The neural mechanisms and circuitry of the pair bond.

Hasse Walum | Larry J Young
Nature reviews. Neuroscience | 2018

Love is one of our most powerful emotions, inspiring some of the greatest art, literature and conquests of human history. Although aspects of love are surely unique to our species, human romantic relationships are displays of a mating system characterized by pair bonding, likely built on ancient foundational neural mechanisms governing individual recognition, social reward, territorial behaviour and maternal nurturing. Studies in monogamous prairie voles and mice have revealed precise neural mechanisms regulating processes essential for the pair bond. Here, we discuss current viewpoints on the biology underlying pair bond formation, its maintenance and associated behaviours from neural and evolutionary perspectives.

Pubmed ID: 30301953

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Associated grants

  • Agency: NIMH NIH HHS, United States
    Id: P50 MH100023
  • Agency: NIH HHS, United States
    Id: P51 OD011132
  • Agency: NIMH NIH HHS, United States
    Id: R01 MH096983
  • Agency: NIMH NIH HHS, United States
    Id: R01 MH112788

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Yerkes National Primate Research Center (tool)

RRID:SCR_001914

Center for advancing scientific understanding and improving the health and well-being of humans and nonhuman primates. The Center conducts research in microbiology and immunology, neurologic diseases, neuropharmacology, behavioral, cognitive and developmental neuroscience, and psychiatric disorders.

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