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Effects of 5HT1A Activation on Depression Profile Following 5-HT Depletion in Rats Lacking Social Attachment Since Weanling.

Kuo-Jung Chang | Yu-Jung Chen | Jing-Yi Chung | Chen-Cheng Lin | Yia-Ping Liu
Psychiatry investigation | 2018

Post weanling isolation-reared (IR) rats are featured with depressive phenotype, yet its mechanism is not clearly defined particularly in terms of the involvement of central 5-HT1A receptors. The present study aims to examine the effects of 5HT1A activation on forced swim test (FST) in IR rats following 5-HT depletion.

Pubmed ID: 30301302

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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