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Magnetic hydrophobic-charge induction adsorbents for the recovery of immunoglobulins from antiserum feedstocks by high-gradient magnetic fishing.

Cláudia Sg Gomes | Adedayo Fashina | Alfred Fernández-Castané | Timothy W Overton | Timothy J Hobley | Eirini Theodosiou | Owen Rt Thomas
Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) | 2018

The extraction of biopharmaceuticals from plasma and serum often employs overly complicated antiquated procedures that can inflict serious damage on especially prone protein targets and which afford low purification power and overall yields. This paper describes systematic development of a high-gradient magnetic fishing process for recovery of immunoglobulins from unclarified antiserum.

Pubmed ID: 30008504

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