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Publication

Siegesbeckia pubescens Makino inhibits Pam3CSK4-induced inflammation in RAW 264.7 macrophages through suppressing TLR1/TLR2-mediated NF-κB activation.

Wei Sang | Zhangfeng Zhong | Kegang Linghu | Wei Xiong | Anfernee Kai Wing Tse | Wai San Cheang | Hua Yu | Yitao Wang
Chinese medicine | 2018

Siegesbeckia pubescens Makino (SP) is one of the important plant origins for the anti-inflammatory Chinese herbal medicine of Siegesbeckiae Herba. The current investigations indicated that the anti-inflammatory effects of SP were associated with the toll-like receptors (TLRs)-mediated nuclear factor-κB (NF-κB) and the mitogen-activated protein kinase (MAPK) signaling pathways.

Pubmed ID: 30002726

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