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Publication

Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes.

An Xie | Anyu Zhou | Hong Liu | Guangbin Shi | Man Liu | Kenneth R Boheler | Samuel C Dudley
PloS one | 2018

Ca2+ release from sarcoplasmic reticulum (SR) is known to contribute to automaticity via the cytoplasmic Na+-Ca2+ exchanger (NCX). Mitochondria participate in Ca2+ cycling. We studied the role of mitochondrial Ca2+ flux in ventricular spontaneous electrical activity.

Pubmed ID: 30001390

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL104025
  • Agency: NHLBI NIH HHS, United States
    Id: R01 HL106592

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This is a list of tools and resources that we have found mentioned in this publication.

MetaMorph Microscopy Automation and Image Analysis Software (tool)

RRID:SCR_002368

Software tool for automated microscope acquisition, device control, and image analysis. Used for integrating dissimilar fluorescent microscope hardware and peripherals into a single custom workstation, while providing all the tools needed to perform analysis of acquired images. Offers user friendly application modules for analysis such as cell signaling, cell counting, and protein expression.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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