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Effect of starvation on brain glucose metabolism and 18F-2-fluoro-2-deoxyglucose uptake: an experimental in-vivo and ex-vivo study.

Ambra Buschiazzo | Vanessa Cossu | Matteo Bauckneht | Annamaria Orengo | Patrizia Piccioli | Laura Emionite | Giovanna Bianchi | Federica Grillo | Anna Rocchi | Francesco Di Giulio | Francesco Fiz | Lizzia Raffaghello | Flavio Nobili | Silvia Bruno | Giacomo Caviglia | Silvia Ravera | Fabio Benfenati | Michele Piana | Silvia Morbelli | Gianmario Sambuceti | Cecilia Marini
EJNMMI research | 2018

The close connection between neuronal activity and glucose consumption accounts for the clinical value of 18F-fluoro-2-deoxyglucose (FDG) imaging in neurodegenerative disorders. Nevertheless, brain metabolic response to starvation (STS) might hamper the diagnostic accuracy of FDG PET/CT when the cognitive impairment results in a severe food deprivation.

Pubmed ID: 29892963

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Associated grants

  • Agency: Compagnia di San Paolo,
    Id: 2015.AAI4110.U4917

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BALB/cAnNCrl (tool)

RRID:MGI:2683685

laboratory mouse with name BALB/cAnNCrl from MGI.

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