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Zika vaccines and therapeutics: landscape analysis and challenges ahead.

Annelies Wilder-Smith | Kirsten Vannice | Anna Durbin | Joachim Hombach | Stephen J Thomas | Irani Thevarjan | Cameron P Simmons
BMC medicine | 2018

Various Zika virus (ZIKV) vaccine candidates are currently in development. Nevertheless, unique challenges in clinical development and regulatory pathways may hinder the licensure of high-quality, safe, and effective ZIKV vaccines.

Pubmed ID: 29871628

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Associated grants

  • Agency: World Health Organization, International
    Id: 001
  • Agency: Horizon 2020 (European Union), International
    Id: 734584

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ClinicalTrials.gov (tool)

RRID:SCR_002309

Registry and results database of federally and privately supported clinical trials conducted in United States and around world. Provides information about purpose of trial, who may participate, locations, and phone numbers for more details. This information should be used in conjunction with advice from health care professionals.Offers information for locating federally and privately supported clinical trials for wide range of diseases and conditions. Research study in human volunteers to answer specific health questions. Interventional trials determine whether experimental treatments or new ways of using known therapies are safe and effective under controlled environments. Observational trials address health issues in large groups of people or populations in natural settings. ClinicalTrials.gov contains trials sponsored by National Institutes of Health, other federal agencies, and private industry. Studies listed in database are conducted in all 50 States and in 178 countries.

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