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Local microRNA-133a downregulation is associated with hypertrophy in the dyssynchronous heart.

Lars B van Middendorp | Marion Kuiper | Chantal Munts | Philippe Wouters | Jos G Maessen | Frans A van Nieuwenhoven | Frits W Prinzen
ESC heart failure | 2017

Left bundle branch block (LBBB) creates considerable regional differences in mechanical load within the left ventricle (LV). We investigated expression of selected microRNAs (miRs) in relation to regional hypertrophy and fibrosis in LBBB hearts and their reversibility upon cardiac resynchronization therapy (CRT).

Pubmed ID: 28772031

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RRID:SCR_003988

Medical technology company that develops and manufactures devices and therapies to treat more than 30 chronic diseases, including heart failure, Parkinson's disease, urinary incontinence, Down syndrome, obesity, chronic pain, spinal disorders, and diabetes. A Commercial healthcare organization for both patients and healthcare professionals. For professionals, it provides products, therapy and procedure solutions, and services.

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