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Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis.

Weam Alshenibr | Mustafa M Tashkandi | Saqer F Alsaqer | Yazeed Alkheriji | Amelia Wise | Sadanand Fulzele | Pushkar Mehra | Mary B Goldring | Louis C Gerstenfeld | Manish V Bais
Arthritis research & therapy | 2017

Lysyl oxidase like-2 (LOXL2) is a copper-dependent amine oxidase. Our previous studies showed that LOXL2 is elevated during mouse fracture healing. The goal of this study was to evaluate the potential of LOXL2 to act as an anabolic agent in cartilage affected by osteoarthritis (OA).

Pubmed ID: 28764769

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: NIDCR NIH HHS, United States
    Id: R03 DE025274
  • Agency: NCATS NIH HHS, United States
    Id: U54 TR001012

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affyPLM (tool)

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