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Light/Dark Shifting Promotes Alcohol-Induced Colon Carcinogenesis: Possible Role of Intestinal Inflammatory Milieu and Microbiota.

Faraz Bishehsari | Abdulrahman Saadalla | Khashayarsha Khazaie | Phillip A Engen | Robin M Voigt | Brandon B Shetuni | Christopher Forsyth | Maliha Shaikh | Martha Hotz Vitaterna | Fred Turek | Ali Keshavarzian
International journal of molecular sciences | 2016

Colorectal cancer (CRC) is associated with the modern lifestyle. Chronic alcohol consumption-a frequent habit of majority of modern societies-increases the risk of CRC. Our group showed that chronic alcohol consumption increases polyposis in a mouse mode of CRC. Here we assess the effect of circadian disruption-another modern life style habit-in promoting alcohol-associated CRC.

Pubmed ID: 27918452

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Associated grants

  • Agency: NIAAA NIH HHS, United States
    Id: R01 AA020216
  • Agency: NIAAA NIH HHS, United States
    Id: R01 AA023417

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MP Biomedicals (tool)

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QIIME (tool)

RRID:SCR_008249

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics.

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