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Publication

Over-expression of calpastatin inhibits calpain activation and attenuates post-infarction myocardial remodeling.

Tingqiao Ye | Qiang Wang | Yan Zhang | Xiaofeng Song | Dachun Yang | De Li | Dan Li | Linan Su | Yongjian Yang | Shuangtao Ma
PloS one | 2015

Calpain is activated following myocardial infarction and ablation of calpastatin (CAST), an endogenous inhibitor of calpains, promotes left ventricular remodeling after myocardial infarction (MI). The present study aimed to investigate the effect of transgenic over-expression of CAST on the post-infarction myocardial remodeling process.

Pubmed ID: 25786109

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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