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Two Antarctic penguin genomes reveal insights into their evolutionary history and molecular changes related to the Antarctic environment.

Cai Li | Yong Zhang | Jianwen Li | Lesheng Kong | Haofu Hu | Hailin Pan | Luohao Xu | Yuan Deng | Qiye Li | Lijun Jin | Hao Yu | Yan Chen | Binghang Liu | Linfeng Yang | Shiping Liu | Yan Zhang | Yongshan Lang | Jinquan Xia | Weiming He | Qiong Shi | Sankar Subramanian | Craig D Millar | Stephen Meader | Chris M Rands | Matthew K Fujita | Matthew J Greenwold | Todd A Castoe | David D Pollock | Wanjun Gu | Kiwoong Nam | Hans Ellegren | Simon Yw Ho | David W Burt | Chris P Ponting | Erich D Jarvis | M Thomas P Gilbert | Huanming Yang | Jian Wang | David M Lambert | Jun Wang | Guojie Zhang
GigaScience | 2014

Penguins are flightless aquatic birds widely distributed in the Southern Hemisphere. The distinctive morphological and physiological features of penguins allow them to live an aquatic life, and some of them have successfully adapted to the hostile environments in Antarctica. To study the phylogenetic and population history of penguins and the molecular basis of their adaptations to Antarctica, we sequenced the genomes of the two Antarctic dwelling penguin species, the Adélie penguin [Pygoscelis adeliae] and emperor penguin [Aptenodytes forsteri].

Pubmed ID: 25671092

Associated grants

  • Agency: Medical Research Council, United Kingdom
    Id: MC_UU_12021/1
  • Agency: Medical Research Council, United Kingdom
    Id: MC_U137761446
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM097251
  • Agency: European Research Council, International
    Id: 249869
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM083127

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This is a list of tools and resources that we have found mentioned in this publication.


PROVEAN (tool)

RRID:SCR_002182

A software tool which predicts whether an amino acid substitution or indel has an impact on the biological function of a protein.

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CAFE (tool)

RRID:SCR_005983

R software package for the detection of gross chromosomal abnormalities from gene expression microarray data.

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miRBase (tool)

RRID:SCR_003152

Central online repository for microRNA nomenclature, sequence data, annotation and target prediction.Collection of published miRNA sequences and annotation.

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RAxML (tool)

RRID:SCR_006086

Software program for phylogenetic analyses of large datasets under maximum likelihood.

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Rfam (tool)

RRID:SCR_007891

The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models (CMs). The families in Rfam break down into three broad functional classes: Non-coding RNA genes, structured cis-regulatory elements and self-splicing RNAs. Typically these functional RNAs often have a conserved secondary structure which may be better preserved than the RNA sequence. The CMs used to describe each family are a slightly more complicated relative of the profile hidden Markov models (HMMs) used by Pfam. CMs can simultaneously model RNA sequence and the structure in an elegant and accurate fashion. Rfam is also available via FTP. You can find data in Rfam in various ways... * Analyze your RNA sequence for Rfam matches * View Rfam family annotation and alignments * View Rfam clan details * Query Rfam by keywords * Fetch families or sequences by NCBI taxonomy * Enter any type of accession or ID to jump to the page for a Rfam family, sequence or genome

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RRID:SCR_011809

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RRID:SCR_011818

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TBLASTN (tool)

RRID:SCR_011822

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WU-BLAST (tool)

RRID:SCR_011824

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RRID:SCR_012954

Software tool that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Currently over 56% of human genomic sequence is identified and masked by the program. Sequence comparisons in RepeatMasker are performed by one of several popular search engines including nhmmer, cross_match, ABBlast/WUBlast, RMBlast and Decypher. RepeatMasker makes use of curated libraries of repeats and currently supports Dfam ( profile HMM library ) and RepBase ( consensus sequence library ).

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PAML (tool)

RRID:SCR_014932

Package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood. PAML estimates parameters and tests hypotheses to study the evolutionary process from a phylogenetic tree.

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SOAPdenovo (tool)

RRID:SCR_014986

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 24,2023. Software tool for de novo assembly of human genomes with massively parallel short read sequencing.Short-read assembly method that can build de novo draft assembly for human sized genomes.Software package for assembling short oligonucleotide into contigs and scaffolds.

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GapCloser (tool)

RRID:SCR_015026

Module of SOAPdenovo2 commonly used independently to close gaps in genome assemblies.

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RepeatModeler (tool)

RRID:SCR_015027

Sequence analysis software that performs repeat family identification and creates models for sequence data. RepeatModeler utilizes RepeatScout and RECON to identify repeat element boundaries and family relationships.

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GeneWise (tool)

RRID:SCR_015054

Gene alignment tool from the EBI which predicts gene structure using similar protein sequences. See also the associated GenomeWise tool.

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CEGMA (tool)

RRID:SCR_015055

THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 19, 2022. Tool to annotate core genes in eukaryotic genomes (that was replaced by BUSCO). Its resulting core gene dataset can be used to train a gene finder or to assess the completeness of the genome or annotations.

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SOAPdenovo (tool)

RRID:SCR_010752

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 24,2023. Software tool for de novo assembly of human genomes with massively parallel short read sequencing.Short-read assembly method that can build de novo draft assembly for human sized genomes.Software package for assembling short oligonucleotide into contigs and scaffolds.

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