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Comparative study of the cytokine/chemokine response in children with differing disease severity in enterovirus 71-induced hand, foot, and mouth disease.

Yan Zhang | Haiying Liu | Linghang Wang | Fan Yang | Yongfeng Hu | Xianwen Ren | Guojun Li | Yu Yang | Shaoxia Sun | Yufen Li | Xinchun Chen | Xingwang Li | Qi Jin
PloS one | 2013

Enterovirus 71 (EV71) infection can lead to a rapidly progressing, life-threatening, and severe neurological disease in young children, including the development of human hand, foot, and mouth disease (HFMD). This study aims to further characterize the specific immunological features in EV71-mediated HFMD patients presenting with differing degrees of disease severity.

Pubmed ID: 23840697

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