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Redistribution of H3K4me2 on neural tissue specific genes during mouse brain development.

Jie Zhang | Jeffrey Parvin | Kun Huang
BMC genomics | 2012

Histone modification plays an important role in cell differentiation and tissue development. A recent study has shown that the dimethylation of lysine 4 residue on histone 3 (H3K4me2) marks the gene body area of tissue specific genes in the human CD4+ T cells and neural cells. However, little is known of the H3k4me2 distribution dynamics through the cell differentiation and tissue development.

Pubmed ID: 23281639

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: 1U01 GM092655-01

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DAVID (tool)

RRID:SCR_001881

Bioinformatics resource system including web server and web service for functional annotation and enrichment analyses of gene lists. Consists of comprehensive knowledgebase and set of functional analysis tools. Includes gene centered database integrating heterogeneous gene annotation resources to facilitate high throughput gene functional analysis.

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