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Publication

Dexamethasone regulates CFTR expression in Calu-3 cells with the involvement of chaperones HSP70 and HSP90.

Luiz Felipe M Prota | Liudmila Cebotaru | Jie Cheng | Jerry Wright | Neeraj Vij | Marcelo M Morales | William B Guggino
PloS one | 2012

Dexamethasone is widely used for pulmonary exacerbation in patients with cystic fibrosis, however, not much is known about the effects of glucocorticoids on the wild-type cystic fibrosis channel transmembrane regulator (CFTR). Our aim was to determine the effects of dexamethasone treatment on wild-type CFTR expression.

Pubmed ID: 23272037

Research resources used in this publication

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: P01 DK072084
  • Agency: NIDDK NIH HHS, United States
    Id: P01:DK72084

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.

Scion Image (tool)

RRID:SCR_008673

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. Commercial software vendor.

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Calu-3 (tool)

RRID:CVCL_0609

Cell line Calu-3 is a Cancer cell line with a species of origin Homo sapiens (Human)

View all literature mentions

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