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VNN1 gene expression levels and the G-137T polymorphism are associated with HDL-C levels in Mexican prepubertal children.

Leonor Jacobo-Albavera | Pablo I Aguayo-de la Rosa | Teresa Villarreal-Molina | Hugo Villamil-Ramírez | Paola León-Mimila | Sandra Romero-Hidalgo | Blanca E López-Contreras | Fausto Sánchez-Muñoz | Rafael Bojalil | Juan Antonio González-Barrios | Carlos A Aguilar-Salinas | Samuel Canizales-Quinteros
PloS one | 2012

VNN1 gene expression levels and the G-137T polymorphism have been associated with high density lipoprotein cholesterol (HDL-C) levels in Mexican American adults. We aim to evaluate the contribution of VNN1 gene expression and the G-137T variant to HDL-C levels and other metabolic traits in Mexican prepubertal children.

Pubmed ID: 23185446

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QUANTO (tool)

RRID:SCR_009084

Software program that computes sample size or power for association studies of genes, environmental factors, gene-environment interaction, or gene-gene interaction. Available study designs for a disease (binary) outcome include the unmatched case-control, matched case-control, case-sibling, case-parent, and case-only designs. Study designs for a quantitative tra it include independent individuals and case parent designs. Quanto is a 32-bit Windows application requiring Windows 95, 98, NT, 2000, ME or XP to run. The graphical user interface allows th e user to easily change the model and view the results without having to edit an input file and rerun the program for every model. The results of a session are stored to a log file. This log can be printed or saved to a file for reviewing at a later date. An option is included to create a text file of the log that can be imported into other documents. (entry from Genetic Analysis Software)

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