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Design, synthesis and biological evaluation of novel betulinic acid derivatives.

Shengjie Yang | Na Liang | Hu Li | Wei Xue | Deyu Hu | Linhong Jin | Qi Zhao | Song Yang
Chemistry Central journal | 2012

Tumor, is one of the major reason for human death, due to its widespread occurrence. Betulinic acid derivatives have attracted considerable attention as cancer chemopreventive agents and also as cancer therapeutics. Many of its derivatives inhibit the growth of human cancer cell lines by triggering apoptosis. With this background, we planned to synthesize a series of betulinic acid derivatives to assess their antiproliferation efficacy on human cancer cell lines.

Pubmed ID: 23174002

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A-375 (tool)

RRID:CVCL_0132

Cell line A-375 is a Cancer cell line with a species of origin Homo sapiens (Human)

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A-431 (tool)

RRID:CVCL_0037

Cell line A-431 is a Cancer cell line with a species of origin Homo sapiens (Human)

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