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After insufficient radiofrequency ablation, tumor-associated endothelial cells exhibit enhanced angiogenesis and promote invasiveness of residual hepatocellular carcinoma.

Jian Kong | Lingqun Kong | Jinge Kong | Shan Ke | Jun Gao | Xuemei Ding | Lemin Zheng | Huichuan Sun | Wenbing Sun
Journal of translational medicine | 2012

The mechanism regarding rapid progression of residual hepatocellular carcinoma (HCC) after insufficient radiofrequency ablation (RFA) has been preliminarily discussed. However, most studies have mainly focused on RFA-induced changes in the tumor cells. The present study was designed to determine whether tumor-associated endothelial cells (TAECs) could contribute to the invasiveness of HCC after insufficient RFA.

Pubmed ID: 23171368

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Hep-G2 (tool)

RRID:CVCL_0027

Cell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HCCLM3 (tool)

RRID:CVCL_6832

Cell line HCCLM3 is a Cancer cell line with a species of origin Homo sapiens (Human)

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