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Publication

Metformin inhibits glutaminase activity and protects against hepatic encephalopathy.

Javier Ampuero | Isidora Ranchal | David Nuñez | María del Mar Díaz-Herrero | Marta Maraver | José Antonio del Campo | Ángela Rojas | Inés Camacho | Blanca Figueruela | Juan D Bautista | Manuel Romero-Gómez
PloS one | 2012

To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients. To analyze the impact of metformin on glutaminase activity and ammonia production in vitro.

Pubmed ID: 23166628

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Caco-2 (tool)

RRID:CVCL_0025

Cell line Caco-2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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