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Recombinant outer capsid glycoprotein (VP7) of rotavirus expressed in insect cells induces neutralizing antibodies in rabbits.

M Khodabandehloo | M Shamsi Shahrabadi | H Keyvani | B Bambai | Za Sadigh
Iranian journal of public health | 2012

Rotaviruses cause diarrhea in infants and young children worldwide. Rotavirus outer capsid protein, VP7 is major neutralizing antigen that is important component of subunit vaccine to prevent rotavirus infection. Many efforts have been done to produce recombinant VP7 that maintain native characteristics. We used baculovirus expression system to produce rotavirus VP7 protein and to study its immunogenicity.

Pubmed ID: 23113180

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NCBI BLAST (tool)

RRID:SCR_004870

Web search tool to find regions of similarity between biological sequences. Program compares nucleotide or protein sequences to sequence databases and calculates statistical significance. Used for identifying homologous sequences.

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BS-C-1 (tool)

RRID:CVCL_0607

Cell line BS-C-1 is a Spontaneously immortalized cell line with a species of origin Chlorocebus pygerythrus (Vervet monkey)

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