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Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells.

Nan You | Weihui Liu | Lijun Tang | Xiao Zhong | Ru Ji | Ning Zhang | Desheng Wang | Yong He | Kefeng Dou | Kaishan Tao
Journal of experimental & clinical cancer research : CR | 2012

Although hypoxia is known to promote hepatoma cell invasion and migration, little is known regarding the molecular mechanisms of this process. Our previous research showed that loss of Tg737 is associated with hepatoma cell invasion and migration; therefore, we hypothesized that the Tg737 signal might be required for hypoxia-enhanced invasion and migration.

Pubmed ID: 22974282

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Hep-G2 (tool)

RRID:CVCL_0027

Cell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)

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