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The influence of therapeutic radiation on the patterns of bone marrow in ovary-intact and ovariectomized mice.

Susanta K Hui | Leslie Sharkey | Louis S Kidder | Yan Zhang | Greg Fairchild | Kayti Coghill | Cory J Xian | Douglas Yee
PloS one | 2012

The functional components of bone marrow (i.e., the hematopoietic and stromal populations) and the adjacent bone have traditionally been evaluated incompletely as distinct entities rather than the integrated system. We perturbed this system in vivo using a medically relevant radiation model in the presence or absence of ovarian function to understand integrated tissue interaction.

Pubmed ID: 22880075

Research resources used in this publication

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Associated grants

  • Agency: NICHD NIH HHS, United States
    Id: K12 HD055887
  • Agency: NIAMS NIH HHS, United States
    Id: 1R03AR055333-01A1
  • Agency: NICHD NIH HHS, United States
    Id: 1K12-HD055887-01
  • Agency: NCI NIH HHS, United States
    Id: R01 CA077398
  • Agency: NIAMS NIH HHS, United States
    Id: R03 AR055333
  • Agency: NCI NIH HHS, United States
    Id: P30 CA77398
  • Agency: NCI NIH HHS, United States
    Id: 1R01CA154491-01
  • Agency: NCI NIH HHS, United States
    Id: R01 CA154491

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Jackson Laboratory (tool)

RRID:SCR_004633

An independent, nonprofit organization focused on mammalian genetics research to advance human health. Their mission is to discover the genetic basis for preventing, treating, and curing human disease, and to enable research for the global biomedical community. Jackson Laboratory breeds and manages colonies of mice as resources for other research institutions and laboratories, along with providing software and techniques. Jackson Lab also conducts genetic research and provides educational material for various educational levels.

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BALB/cAnNCrl (tool)

RRID:MGI:2683685

laboratory mouse with name BALB/cAnNCrl from MGI.

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