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Publication

Mucosal healing and fibrosis after acute or chronic inflammation in wild type FVB-N mice and C57BL6 procollagen α1(I)-promoter-GFP reporter mice.

Shengli Ding | Kristen L W Walton | Randall Eric Blue | Kirk K McNaughton | Scott T Magness | Pauline Kay Lund
PloS one | 2012

Injury and intestinal inflammation trigger wound healing responses that can restore mucosal architecture but if chronic, can promote intestinal fibrosis. Intestinal fibrosis is a major complication of Crohn's disease. The cellular and molecular basis of mucosal healing and intestinal fibrosis are not well defined and better understanding requires well characterized mouse models.

Pubmed ID: 22880035

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Associated grants

  • Agency: NIEHS NIH HHS, United States
    Id: P30 ES010126
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK047769
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK047769-12

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.

Novus Biologicals (tool)

RRID:SCR_004286

Commercial antibody vendor which supplies antibodies and other products to life science researchers.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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