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Publication

Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury.

Ivan Bohacek | Pierre Cordeau | Mélanie Lalancette-Hébert | Dunja Gorup | Yuan-Cheng Weng | Srecko Gajovic | Jasna Kriz
Journal of neuroinflammation | 2012

Using a live imaging approach, we have previously shown that microglia activation after stroke is characterized by marked and long-term induction of the Toll-like receptor (TLR) 2 biophotonic signals. However, the role of TLR2 (and potentially other TLRs) beyond the acute innate immune response and as early neuroprotection against ischemic injury is not well understood.

Pubmed ID: 22873409

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Associated grants

  • Agency: Canadian Institutes of Health Research, Canada

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